Clinical Biochemistry

BÜHLMANN Gamma-hydroxybutyric acid (GHB)

The quantitative detection of the abuse/intoxication of gamma-hydroxybutyric acid (GHB) also known as liquid ecstasy is still a challenge in toxicology. To date, GHB is not detected by routine blood or urine drug screens. Its detection is virtually only possible with chromatographic methods.

These methods are time-consuming and laborious since they often require derivatization of the drug and/or sample extraction. Therefore, many cases involving GHB may be missed in hospitals and forensic institutes. This situation causes a permanent under-estimation of the amount of this kind of severe intoxications or the inappropriate care of victims. Clearly, there is a requirement for simple and rapid analytical procedures to meet current increased demand for analysis. The BÜHLMANN enzymatic GHB assay will allow a direct, quick and easy quantification of exogenous intake of GHB.

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