Microbiology

Latex agglutination test on slide for the qualitative and semi-quantitative determination of specific Infectious Mononucleosis heterophile antibodies in serum or plasma. The Monogen reagent is a suspension of polystyrene latex particles of uniform size coated with highly purified Paul-Bunnell antigen from bovine red cell membranes. The degree of purity of the antigen is such that Monogen only reacts with Infectious Mononucleosis heterophile antibodies. For this reason, “differential” absorptions are not necessary. Latex particles allow visual observation of the antigen-antibody reaction. If Infectious Mononucleosis heterophile antibodies are present in the sample, the latex suspension changes its uniform appearance, and a clear agglutination becomes evident.